What Happened After Alexander the Great’s Death?

Alexander the Great built a grand empire, but it fell apart after his death. Discover what happened after Alexander the Great's death.

Published: Jun 8, 2026 written by Mike Cohen, BA History

death of alexander the great

 

In June 323 BC, Alexander the Great died at just 32 years of age while at his palace in Babylon, likely from an illness. His sudden death created a huge power vacuum across his vast new empire. He had left no clear heir, and his wife, Roxana, was pregnant. No one knew if the child would be a boy. His only other family was a half-brother, Philip III, who was not considered mentally fit to rule. What happened after Alexander the Great’s death that would shape the Hellenistic world for the next century?

 

The Immediate Aftermath of Alexander the Great’s Death

alexander the great bust
Marble portrait head of Alexander the Great, c. 1st century BC. Source: British Museum

 

Alexander’s illness took 12 days to kill him, giving the people around him time to consider the succession problem. With no suitable biological heir, his close retinue of commanders and generals looked to themselves. But when they asked the general to indicate who should succeed him, he reportedly replied with the cyrptic statement “to the strongest.”

 

In the end, the Macedonian court at Babylon agreed that Philip III and Roxana and Alexander’s unborn child (who would be a boy, Alexander IV) would be kings together. Perdiccas, Alexander’s trusted subordinate, was to oversee the succession as a regent as the two were just kings in name. This agreement, known as the Partition of Babylon, was not reached peacefully. The common soldiers reportedly wanted stability and therefore favored the adult Philip III, while the cavalry, led by Perdiccas, preferred Alexander’s unborn child, presumably because he would be easy to control. The infantry seized the palace, forcing the compromise.

 

 

The Diadochi & Division of Power

battle of issus mosaic alexander the great
Detail from the Battle of Issus mosaic of Alexander the Great and his horse Bucephalus, 100 BC. Source: Archaeological Museum of Napoli

 

To protect himself from Alexander’s other powerful generals, Perdiccas made them satraps (governors) of the different regions of the empire. Ptolemy was given Egypt, Antigonus I Monophthalmus got a big part of modern-day Turkey, Lysimachus got Thrace, Antipater and Craterus were given Macedon and Greece, and Eumenes Cappadocia. Perdiccas sent them off to get them out of the way, but he was essentially giving each a private kingdom, where they could build armies.

 

This settlement lasted less than two years, as Perdiccas tried to assert his power as supreme ruler and the generals, who became known as the Diadochi, assertedtheir independence.

 

The first major conflict started when Ptolemy, who was already building his power in Egypt, and also claimed to be the conquerors half-brother. He rerouted Alexander the Great’s funeral procession to take control of his body. Ptolemy knew this was a powerful relic to possess, so he took it to Memphis and robbed Perdiccas of the right to bury the king. This led to the First War of the Successors in 322 BC.

 

 

The First War of the Successors

alexander-iv-stater
Stater of Alexander IV (obverse side) and Philip III (reverse side), 4th century BC. Source: Yale University Art Gallery

 

In the First War of the Successors, Perdiccas marched to Egypt to punish Ptolemy for taking Alexander’s body, but was met with strong resistance. After he failed to cross the Nile River, his own officers, including Seleucus, a Macedonian Greek general, turned against him and killed him in 321 BC. The death of Perdiccas was the true end of any central power holding together Alexander’s empire.

 

The empire was now a free-for-all and the wars that followed were a messy series of deals and betrayals. The main goal of each warlord was no longer to serve the empire but to cut out the biggest kingdom for himself. The most powerful of these was Antigonus I Monophthalmus who, with his son Demetrius, came closest to putting Alexander’s lands back together in a 20-year war across the Middle East and Greece.

 

 

Key Players in the Succession Wars

PlayerOriginal Role under AlexanderTerritory Claimed / Controlled
Ptolemy I SoterGeneral, Close Friend, and BodyguardEgypt, Libya, and parts of Syria
Seleucus I NicatorCommander of the elite “Silver Shields” infantryBabylonia, Persia, and Central Asia (The East)
CassanderSon of Regent Antipater (Did not campaign in Asia)Macedonia and parts of Greece
Antigonus I Monophthalmus (One-Eye)Veteran General and Satrap of PhrygiaAsia Minor, Syria, and Mesopotamia
Demetrius I Poliorcetes (The Besieger)General and Admiral (Son of Antigonus One-Eye)Greece, the Aegean, and later Macedonia
LysimachusPersonal Bodyguard and GeneralThrace and Western Asia Minor
PerdiccasSupreme Commander of Cavalry / Right-hand manThe entire Empire (as Regent)
Eumenes of CardiaChief Royal Secretary and CommanderCentral Asia Minor (Cappadocia)

 

End of the Argead Dynasty

Royal Lineage of Macedon: The Argead Dynasty. Source: TheCollector
Royal Lineage of Macedon: The Argead Dynasty.

 

While the generals fought for land, the remaining members of Alexander’s family were used as pawns. Their royal blood made them both useful and a threat to the generals with regal ambitions. In 317 BC, Alexander’s mother, Olympias, had his half-brother Philip III and his wife killed. The act showed just how ruthless the time was.

 

One of the generals, Cassander, son of Antipater, took control of Macedonia. He feared the claim of Alexander’s real heir and so he locked up the young Alexander IV and his mother, Roxana, around 310 BC. He then had them secretly murdered.

 

The move ended the Argead family line that had ruled Macedonia for hundreds of years. With the royal family gone, the leadership claims through Alexander’s bloodline subsided. Antigonus, Ptolemy, Seleucus, and the other top generals all began calling themselves kings of their own lands. This made the breakup of the empire official.

 

 

The Battle of Ipsus

three ancient marble busts ptolemy seleucus lysimachus
Marble busts of: Lysimachus, Hellenistic c. 300 BC, via Wikimedia Commons (Left); Ptolemy, Hellenistic c. 305 BC, via The Louvre (Center); Seleucus, Roman 1st-2nd Century AD, via the Louvre (Right)

 

The great ambition of Antigonus to be the one true ruler led to a final team-up against him. The final battle of the Succession Wars, called the Battle of Ipsus, took place in 301 BC near Ipsus in modern-day Turkey. The joint armies of Lysimachus, Cassander, and Seleucus, who brought war elephants from his battles in India, went up against the army of Antigonus. The 81-year-old Antigonus fought bravely but was killed on the battlefield. His death at Ipsus was the end of the endeavor of one big empire. The winners split his huge territories among themselves. The change created a new map of the Hellenistic world and ended any real chance of putting the initial territories ruled by Alexander the Great back together.

 

As such, the death of Alexander the Great did not lead to one new ruler, but to a violent imperial collapse. The legacy of the successors was the creation of a new Hellenistic world that was a vibrant, mixed-culture society where the Greek language and ideas blended with the cultures of the East.

 

Succession Wars Timeline

Year (BC)EventSummary
323Death of Alexander & Partition of Babylon
Alexander dies in Babylon. The Partition of Babylon establishes the disabled Philip III and the unborn Alexander IV as joint puppet kings, with Perdiccas as Regent.
322–321The First War of the Successors
Triggered by Ptolemy hijacking Alexander’s body and Perdiccas’s growing ambition. Perdiccas invades Egypt but is assassinated by his own officers.
321Treaty of Triparadisus
The empire is re-carved. Antipater becomes the new Regent and takes the puppet kings to Macedonia. Seleucus is rewarded with the governorship of Babylon.
319–315The Second War of the Successors
Antipater dies, sparking a civil war in Macedonia between his son Cassander and the new regent Polyperchon. Antigonus defeats and executes Eumenes, becoming the most powerful general.
314–311The Third War of the Successors
The other generals form a grand coalition to stop the rapid expansion of Antigonus. Peace in 311, which recognizes Cassander’s control of Macedonia until Alexander’s young son comes of age.
310–309Extinction of the Argead Dynasty
Cassander secretly murders Alexander’s 14-year-old son (Alexander IV) and his mother Roxana. Shortly after, Alexander’s illegitimate son Heracles is also murdered.
308–301The Fourth War of the Successors
Antigonus and his son Demetrius try one last time to fully reunite Alexander’s empire. In 306–305 BCE, the remaining generals all formally crown themselves Kings of their respective regions.
301The Battle of Ipsus
Known as the “Battle of the Kings,” Antigonus is killed, ending any hope of a unified empire.
288–285The Fall of Demetrius
Demetrius (son of Antigonus) seizes Macedonia but is driven out by a joint invasion. He launches a desperate campaign in Asia Minor but is captured by Seleucus and drinks himself to death in luxurious captivity.
281The Battle of Corupedium
The elderly Seleucus defeats and kills the elderly Lysimachus. Months later, Seleucus is assassinated, marking the definitive end of the Successor generation.

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Mike CohenBA History

Mike is Bachelor of Arts History graduate from the University of Leeds. As a historian, he loves to write about historical figures and events, especially those that continue to influence the modern world.